1,205 research outputs found

    Fairies

    Get PDF

    Implications for alcohol minimum unit pricing advocacy: what can we learn for public health from UK newsprint coverage of key claim-makers in the policy debate?

    Get PDF
    On May 24th 2012, Scotland passed the Alcohol (Minimum Pricing) Bill. Minimum unit pricing (MUP) is an intervention that raises the price of the cheapest alcohol to reduce alcohol consumption and related harms. There is a growing literature on industryā€™s influence in policymaking and media representations of policies, but relatively little about frames used by key claim-makers in the public MUP policy debate. This study elucidates the dynamic interplay between key claim-makers to identify lessons for policy advocacy in the media in the UK and internationally. Content analysis was conducted on 262 articles from seven UK and three Scottish national newspapers between 1st May 2011 and 31st May 2012, retrieved from electronic databases. Advocatesā€™ and criticsā€™ constructions of the alcohol problem and MUP were examined. Advocates depicted the problem as primarily driven by cheap alcohol and marketing, while criticsā€™ constructions focused on youth binge drinkers and dependent drinkers. Advocates justified support by citing the interventionā€™s targeted design, but critics denounced the policy as illegal, likely to encourage illicit trade, unsupported by evidence and likely to be ineffective, while harming the responsible majority, low-income consumers and businesses. Criticsā€™ arguments were consistent over time, and single statements often encompassed multiple rationales. This study presents advocates with several important lessons for promoting policies in the media. Firstly, it may be useful to shift focus away from young binge drinkers and heavy drinkers, towards population-level over-consumption. Secondly, advocates might focus on presenting the policy as part of a wider package of alcohol policies. Thirdly, emphasis on the success of recent public health policies could help portray the UK and Scotland as world leaders in tackling culturally embedded health and social problems through policy; highlighting past successes when presenting future policies may be a valuable tactic both within the UK and internationally

    Representations of minimum unit pricing for alcohol in UK newspapers: a case study of a public health policy debate

    Get PDF
    Background: Mass media influence public acceptability, and hence feasibility, of public health interventions. This study investigates newsprint constructions of the alcohol problem and minimum unit pricing (MUP). Methods: Quantitative content analysis of 901 articles about MUP published in 10 UK and Scottish newspapers between 2005 and 2012. Results: MUP was a high-profile issue, particularly in Scottish publications. Reporting increased steadily between 2008 and 2012, matching the growing status of the debate. The alcohol problem was widely acknowledged, often associated with youths, and portrayed as driven by cheap alcohol, supermarkets and drinking culture. Over-consumption was presented as a threat to health and social order. Appraisals of MUP were neutral, with supportiveness increasing slightly over time. Arguments focused on health impacts more frequently than more emotive perspectives or business interests. Health charities and the NHS were cited slightly more frequently than alcohol industry representatives. Conclusion: Emphases on efficacy, evidence and experts are positive signs for evidence-based policymaking. The high profile of MUP, along with growing support within articles, could reflect growing appetite for action on the alcohol problem. Representations of the problem as structurally driven might engender support for legislative solutions, although cultural explanations remain common

    A quantitative content analysis of UK newsprint coverage of proposed legislation to prohibit smoking in private vehicles carrying children

    Get PDF
    This project was funded by Cancer Research UK (MC_U130085862) and the Scottish School of Public Health Research. Cancer Research UK and the Scottish School of Public Health Research were not involved in the collection, analysis, and interpretation of data, writing of the manuscript or the decision to submit the manuscript for publication. Shona Hilton, Karen Wood and Chris Patterson were funded by the UK Medical Research Council as part of the Understandings and Uses of Public Health Research programme (MC_UU_12017/6) at the MRC/CSO Social and Public Health Sciences Unit, University of Glasgow. Thanks to Josh Bain and Alan Pollock for coding assistance.Peer reviewedPublisher PD

    How men and women learn about sex: multi-generational perspectives on insufficient preparedness and prevailing gender norms in Scotland

    Get PDF
    Attitudes towards sexual health and relationships are learned from a young age, and there is an ongoing need for innovative and comprehensive approaches to sex education that keep pace with rapidly changing contexts of peopleā€™s lives. We used thematic analysis of data from two qualitative studies in Scotland to explore learning contexts from a multi-generational perspective, as well as the influence of different socio-cultural factors on provision, access to and experience of sex education. The importance, but inadequacy, of school as a source of learning, was a persistent theme over time. Participantsā€™ strategies to address perceived gaps in knowledge included experience, conversations, vicarious and online learning. Gender and age differences emerged, with younger participants more likely to go online for information, and prevailing gender norms shaping attitudes and behaviours across both study groups. Participants who identified as gay, lesbian or bisexual described feeling particularly unprepared for sex and relationships due to the narrow, heteronormative content received. Although schools continue to be a common source of information, it appears that they fail to equip young people for their post-school sexual life-course. We recommend the mandatory provision of comprehensive, positive, inclusive and skills-based learning to improve peopleā€™s chances of forming and building healthy, positive relationships across the lifespan

    Regulation of signaling genes by TGFĪ² during entry into dauer diapause in C. elegans

    Get PDF
    BACKGROUND: When resources are scant, C. elegans larvae arrest as long-lived dauers under the control of insulin/IGF- and TGFĪ²-related signaling pathways. However, critical questions remain regarding the regulation of this developmental event. How do three dozen insulin-like proteins regulate one tyrosine kinase receptor to control complex events in dauer, metabolism and aging? How are signals from the TGFĪ² and insulin/IGF pathways integrated? What gene expression programs do these pathways regulate, and how do they control complex downstream events? RESULTS: We have identified genes that show different levels of expression in a comparison of wild-type L2 or L3 larvae (non-dauer) to TGFĪ² mutants at similar developmental stages undergoing dauer formation. Many insulin/IGF pathway and other known dauer regulatory genes have changes in expression that suggest strong positive feedback by the TGFĪ² pathway. In addition, many insulin-like ligand and novel genes with similarity to the extracellular domain of insulin/IGF receptors have altered expression. We have identified a large group of regulated genes with putative binding sites for the FOXO transcription factor, DAF-16. Genes with DAF-16 sites upstream of the transcription start site tend to be upregulated, whereas genes with DAF-16 sites downstream of the coding region tend to be downregulated. Finally, we also see strong regulation of many novel hedgehog- and patched-related genes, hormone biosynthetic genes, cell cycle genes, and other regulatory genes. CONCLUSIONS: The feedback regulation of insulin/IGF pathway and other dauer genes that we observe would be predicted to amplify signals from the TGFĪ² pathway; this amplification may serve to ensure a decisive choice between "dauer" and "non-dauer", even if environmental cues are ambiguous. Up and down regulation of insulin-like ligands and novel genes with similarity to the extracellular domain of insulin/IGF receptors suggests opposing roles for several members of these large gene families. Unlike in adults, most genes with putative DAF-16 binding sites are upregulated during dauer entry, suggesting that DAF-16 has different activity in dauer versus adult metabolism and aging. However, our observation that the position of putative DAF-16 binding sites is correlated with the direction of regulation suggests a novel method of achieving gene-specific regulation from a single pathway. We see evidence of TGFĪ²-mediated regulation of several other classes of regulatory genes, and we discuss possible functions of these genes in dauer formation

    Granulomatous inflammation in tuberculosis and sarcoidosis: does the lymphatic system contribute to disease?

    Get PDF
    A striking and unexplained feature of granulomatous inflammation is its anatomical association with the lymphatic system. Accumulating evidence suggests that lymphatic tracks and granulomas may alter the function of each other. The formation of new lymphatics, or lymphangiogenesis, is an adaptive response to tumor formation, infection, and wound healing. Granulomas also may induce lymphangiogenesis which, through a variety of mechanisms, could contribute to disease outcomes in tuberculosis and sarcoidosis. On the other hand, alterations in lymph node function and lymphatic draining may be primary events which attenuate the risk and severity of granulomatous inflammation. This review begins with an introduction of granulomatous inflammation and the lymphatic system. A role of the lymphatic system in tuberculosis and sarcoidosis is then hypothesized. With a focus on lymphangiogenesis in these diseases, and on the potential for this process to promote dissemination, parallels are established with the wellā€established role of lymphangiogenesis in tumor biology

    Brain growth: Intuitive and scientific

    Get PDF
    Developmental processes of the brain have long been considered the last frontier by scientists as well as educators. There has been much speculation concerning how and when the mind grows and if intellectual growth appears at the same time the skull and brain are physiologically and neurologically growing. Prior to recent research many educators assumed that learning, or intellectual advancement, occurred in an almost continuous manner. Educators felt children built skill upon skill and constantly moved from one stage of cognitive development to the next higher level of cognitive development. Traditionally, educational systems have been based on this concept of continuous intellectual development

    Making education and career decisions : school students' aspirations, attitudes and influences

    Get PDF
    The study investigated the ways that Year 10 and Year 12 students make education and career decisions, the processes that they draw on in arriving at these decisions, and critical factors that influence their thinking about a range of study and career issues. It was commissioned by the Department of Education, Science and Training and conducted in New South Wales, Queensland and Western Australia. In examining decision-making processes, the study paid particular attention to the influence of Career Advisers, the uptake and reception of Vocational Education and Training in schools, attitudes to traditional trades and school-based New Apprenticeships, and current thinking about teaching as a career. Each of these themes was considered from the perspective of students, parents, Career Advisers and Principals. Importantly, the study examined whether decision-making of this kind was associated with studentsā€™ gender, and with the socio-economic and geographical demographics of the schools that students attended. Some of the main findings determined that: ā€¢ parents are the most significant influence on the formation of studentsā€™ career aspirations; ā€¢ career advisers are less influential but very important in helping students to clarify their options and pathways to achieve them; ā€¢ 60% of students aimed to go to university and 20% to VET courses (including apprenticeships), reflecting studentsā€™ hope of a career in professional occupations; ā€¢ VET opportunities are not well understood by many students; and ā€¢ teaching is not a first choice profession for a variety of reasons, especially among males
    • ā€¦
    corecore